Article
Association between METTL3 gene polymorphisms and neuroblastoma susceptibility: A nine-centre case-control study.
Journal of cellular and molecular medicine - 1 Aug 2020
Bian Jun, Zhuo Zhenjian, Zhu Jinhong, Yang Zhonghua, Jiao Zhang, Li Yong, Cheng Jiwen, Zhou Haixia, Li Suhong, Li Li, He Jing, Liu Yanfei
Abstract excerpt
Neuroblastoma ranks as the most commonly seen and deadly solid tumour in infancy. The aberrant activity of m6 A-RNA methyltransferase METTL3 is involved in human cancers. Therefore, functional genetic variants in the METTL3 gene may contribute to neuroblastoma risk. In the current nine-centre case-control study, we aimed to analyse the association between the METTL3 gene single nucleotide polymorphisms (SNPs) and...
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