Article
Regulome-wide association study identifies genetically driven accessible regions associated with pancreatic cancer risk.
International journal of cancer - 15 Feb 2024
Liu Shuai, Zhong Hua, Zhu Jingjing, Wu Yong, Deng Youping, Wu Lang
Abstract excerpt
Genome-wide association studies (GWAS) have identified two dozen genetic variants that are associated with the risk of pancreatic ductal adenocarcinoma (PDAC), a deadly malignancy. However, a majority of these variants are located in noncoding regions of the genome, which limits the translation of GWAS findings into clinical applications. The regulome-wide association study (RWAS) is a recently developed method...
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