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Article

A Transcriptome-Wide Association Study Identifies Candidate Susceptibility Genes for Pancreatic Cancer Risk.

Cancer research - 15 Oct 2020

Liu Duo, Zhou Dan, Sun Yanfa, Zhu Jingjing, Ghoneim Dalia, Wu Chong, Yao Qizhi, Gamazon Eric R, Cox Nancy J, Wu Lang

Abstract excerpt

Pancreatic cancer is among the most well-characterized cancer types, yet a large proportion of the heritability of pancreatic cancer risk remains unclear. Here, we performed a large transcriptome-wide association study to systematically investigate associations between genetically predicted gene expression in normal pancreas tissue and pancreatic cancer risk. Using data from 305 subjects of mostly European...

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Identifiers

PMID: 32907841
DOI: 10.1158/0008-5472.CAN-20-1353
PMCID: PMC7572664

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