Article
Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.
Carcinogenesis - 19 Aug 2021
Pistoni Laura, Gentiluomo Manuel, Lu Ye, López de Maturana Evangelina, Hlavac Viktor, Vanella Giuseppe, Darvasi Erika, Milanetto Anna Caterina, Oliverius Martin, Vashist Yogesh, Di Leo Milena, Mohelnikova-Duchonova Beatrice, Talar-Wojnarowska Renata, Gheorghe Cristian, Petrone Maria Chiara, Strobel Oliver, Arcidiacono Paolo Giorgio, Vodickova Ludmila, Szentesi Andrea, Capurso Gabriele, Gajdán László, Malleo Giuseppe, Theodoropoulos George E, Basso Daniela, Soucek Pavel, Brenner Hermann, Lawlor Rita T, Morelli Luca, Ivanauskas Audrius, Kauffmann Emanuele Federico, Macauda Angelica, Gazouli Maria, Archibugi Livia, Nentwich Michael, Loveček Martin, Cavestro Giulia Martina, Vodicka Pavel, Landi Stefano, Tavano Francesca, Sperti Cosimo, Hackert Thilo, Kupcinskas Juozas, Pezzilli Raffaele, Andriulli Angelo, Pollina Luca, Kreivenaite Edita, Gioffreda Domenica, Jamroziak Krzysztof, Hegyi Péter, Izbicki Jakob R, Testoni Sabrina Gloria Giulia, Zuppardo Raffaella Alessia, Bozzato Dania, Neoptolemos John P, Malats Núria, Canzian Federico, Campa Daniele
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers. Its poor prognosis is predominantly due to the fact that most patients remain asymptomatic until the disease reaches an advanced stage, alongside the lack of early markers and screening strategies. A better understanding of PDAC risk factors is essential for the identification of groups at high risk in the population. Genome-wide...
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