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Pancreatic cancer prognosis is predicted by a novel ATAC-array technology for assessing chromatin accessibility

2021-01-22

Abstract excerpt

We investigated tumor-cell-intrinsic chromatin accessibility patterns of pancreatic ductal adenocarcinoma (PDAC) by ATAC-seq on EpCAM + PDAC malignant epithelial cells, sorted from 54 freshly resected human tumors, and discovered a signature of 1092 chromatin loci displaying differential accessibility between patients with disease free survival (DFS) < 1 year and patients with DFS > 1 year. Analyzing transcriptio...

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Literature Corpus work
e0c381f1-abc3-50e1-8455-a71b19a1ff03
DOI
10.1101/2021.01.21.427604
Open publication

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Pancreatic cancer prognosis is predicted by a novel ATAC-array technology for assessing chromatin accessibilityDOI 10.1101/2021.01.21.427604
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