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Article

Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes

11 May 2018

Abstract excerpt

Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although there remains a lack of knowledge regarding the underlying epigenomics of PDAC. Here we perform multi-parametric integrative analyses of chromatin immunoprecipitation-sequencing (ChIP-seq) on multiple histone modifications, RNA-sequencing (RNA-seq), and DNA...

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PMID: 29773832
DOI: 10.1038/s41467-018-04383-6

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