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Article

Incidence of Dementia and Alzheimer's Disease, Genetic Susceptibility, and Grip Strength Among Older Adults.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Mar 2024

Kim Youngwon, Wang Mengyao, Sharp Stephen J, Au Yeung Shiu Lun, Luo Shan, Jang Haeyoon, Jiesisibieke Zhu Liduzi, Shi Qiaoxin, Chen Ziyuan, Brage Soren

Abstract excerpt

BACKGROUND: Grip strength has prognostic value for aging-related health outcomes. Whether the associations of grip strength with the risk of dementia and Alzheimer's disease (AD) vary by the genetic risk of AD and related dementias (ADD) is unknown. METHODS: This study included 148 659 older adults of white British ancestry (aged ≥60 years) participating in UK Biobank with no dementia, and self-reported poor...

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PMID: 37804123
DOI: 10.1093/gerona/glad224
PMCID: PMC10851673

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