Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical function

1 Jun 2018

Abstract excerpt

Neurodegenerative disorders are associated with impaired cognitive function and worse physical health outcomes. This study aims to test whether polygenic risk for Alzheimer's disease, Amyotrophic Lateral Sclerosis (ALS), or frontotemporal dementia (FTD) is associated with cognitive function and physical health in the UK Biobank, a cohort of healthy individuals. Group-based analyses were then performed to compare...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Bioinformatics and Genomic Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29856801
DOI: 10.1371/journal.pone.0198187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical functionPMID 29856801Read ↗

Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical functionSemantic proximity Read ↗

Use of an Alzheimer’s disease polygenic risk score to identify mild cognitive impairment in adults in their 50sSemantic proximity Read ↗

Assessment of genetic risk for improved clinical-neuropathological correlations.Semantic proximity Read ↗

Polygenic Liability to Alzheimer's Disease Is Associated with a Wide Range of Chronic Diseases: A Cohort Study of 312,305 Participants.Semantic proximity Read ↗

Predicting risk of Alzheimer’s disease using polygenic risk scores developed for Parkinson’s diseaseSemantic proximity Read ↗

Incidence of Dementia and Alzheimer's Disease, Genetic Susceptibility, and Grip Strength Among Older Adults.Semantic proximity Read ↗

Genetic risk for Alzheimer’s disease influences neuropathology and cognition via multiple biological pathwaysSemantic proximity Read ↗

The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomizationSemantic proximity Read ↗

Genetic risk in Alzheimer's disease.Semantic proximity Read ↗

Association of genetic risk of Alzheimer's disease and cognitive function in two European populations.Semantic proximity Read ↗

A non- <i>APOE</i> Polygenic score for Alzheimer’s disease and <i>APOE-ε4</i> have independent associations with dementia in the Health and Retirement StudySemantic proximity Read ↗

Genetic risk factor clustering within and across neurodegenerative diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.