Article

From genome to phenome via the proteome: broad capture, antibody-based proteomics to explore disease mechanisms

2022-08-22

Abstract excerpt

Studying the plasma proteome as the intermediate layer between the genome and the phenome has the potential to identify disease causing genes and proteins and to improve our understanding of the underlying mechanisms. Here, we conducted a cis -focused proteogenomic analysis of 2,923 plasma proteins measured in 1,180 individuals using novel antibody-based assays (Olink® Explore 1536 and Explore Expansion) to identi...

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Literature Corpus work: 65d0b9e0-82c0-5407-8b21-09c9a19cd83b
DOI: 10.1101/2022.08.19.22278984

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