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Article

Elucidation of the structural dynamics of mutations in PHB2 protein associated with growth suppression and cancer progression.

Gene - 10 Jan 2024

Khatua Susmita, Roy Alankar, Sen Pritha, Ray Sujay

Abstract excerpt

Prohibitin is a multifunctional protein that plays an important role in numerous cellular processes. Membrane-associated mitochondrial prohibitin complex is made up of two subunits, PHB1 and PHB2 which are ubiquitously expressed and analogous to each other. High levels of prohibitin expression have consequently been found in esophageal cancer, endometrial adenocarcinoma, gastric cancer, hepatocellular carcinoma,...

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Source

Identifiers

PMID: 37739195
DOI: 10.1016/j.gene.2023.147820

Genes

PHB2
PHB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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