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Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to treat breast cancer - a computational approach.

Advances in protein chemistry and structural biology - 1 Jan 2021

Thirumal Kumar D, Udhaya Kumar S, Magesh R, George Priya Doss C

Abstract excerpt

Membrane proteins are the most common types of cancer that are active in the prognosis. Membrane proteins are a distinguishing characteristic of a cancer cell. In tumor cell therapy, the overexpressed membrane proteins are becoming ever more relevant. The 3-kinase (PI3K)/AKT phosphatidylinositol pathway is downstream triggered by different extracellular signals, and this signaling pathway activation impacts a...

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Share to Breast Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33485488
DOI: 10.1016/bs.apcsb.2020.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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