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Article

Systematic transition modeling analysis in the MEF2B-DNA binding interface due to Y69H and K4E variants.

Journal of molecular graphics & modelling - 1 Nov 2021

Zia Ayisha, Rashid Sajid

Abstract excerpt

Transcriptional coactivator myocyte enhancer factor 2B (MEF2B) mutations are the most common cause of germinal center-derived B-cell non-Hodgkin lymphoma. Despite well-established contributions in lymphomagenesis, the structure-function paradigms of these mutations are largely unknown. Here through in silico approaches, we present structural evaluation of two reported missense variants (K4E and Y69H) in MEF2B to...

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Identifiers

PMID: 34418874
DOI: 10.1016/j.jmgm.2021.108009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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