Article
Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers
20 Sept 2023
Abstract excerpt
Abstract Background Systemic and local profiles have each been associated with asthma, but parsing causal relationships between system-wide and airway-specific processes can be challenging. We sought to investigate systemic and airway processes in asthma and their causal relationships. Methods Three hundred forty-one participants with persistent asthma and non-asthmatic controls were recruited and underwent...
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