Article
Pathway analysis of genome-wide association study on asthma.
Human immunology - 1 Feb 2013
Song Gwan Gyu, Lee Young Ho
Abstract excerpt
OBJECTIVE: The aims of this study were to identify the candidate causal single nucleotide polymorphisms (SNPs) and candidate causal mechanisms of asthma and to generate SNP to gene to pathway hypotheses. METHODS: SNPs that met a threshold of p ≤ 0.001 in a genome-wide association study (GWAS) dataset of asthma, which included 292,443 SNPs in 473 asthma cases and 1892 controls, were used in the present study....
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