Article

Integration of Airway Inflammation and Remodeling Mechanisms Specific to Eosinophilic Asthma Through Differential Co-Expression of Genes in Bronchial Brush Biopsy Samples

2021-02-24

Abstract excerpt

<h4>Background: </h4> Heterogeneity of asthma complicates search for targeted treatment against airway hyperresponsiveness and remodeling. We conducted a systems biology approach study to establish differential co-expression of genes (DCG) in eosinophilic and non-eosinophilic asthma patients and infer their role in the disease. Materials and Methods N = 40 Caucasian adult moderate to severe non-smoking asthma pat...

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Literature Corpus work: fc261fd9-252e-577b-9287-20bade5295ab
DOI: 10.21203/rs.3.rs-228649/v1

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