Genetic associations between asthma and type 2 inflammatory diseases: Insights from pleiotropic loci and genes: shared genetics of Type 2 Iinflammatory diseases: Shared Genetics of Type 2 Inflammatory Diseases.

Abstract excerpt

BACKGROUND: Type 2 inflammatory diseases (T2IDs) often coexist, but their shared genetic basis remains unclear. This study explores common genetic basis between asthma and other T2IDs and identifies pleiotropic loci and mechanisms. METHODS: Using genome-wide association study (GWAS) summary statistics, we assessed genetic correlation between asthma and four T2IDs (allergic conjunctivitis [AC], allergic rhinitis...

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