Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma

22 May 2023

Abstract excerpt

Abstract Rationale Indirect airway hyperresponsiveness (AHR) is a highly specific feature of asthma, but the underlying mechanisms responsible for driving indirect AHR remain incompletely understood. Objectives To identify differences in gene expression in epithelial brushings obtained from individuals with asthma who were characterized for indirect AHR in the form of exercise-induced bronchoconstriction (EIB)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergic Rhinitis and Sensitization
Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37212596
DOI: 10.1164/rccm.202209-1707oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in AsthmaPMID 37212596Read ↗

Epithelial and immune transcriptomic characteristics and possible regulatory mechanisms in asthma exacerbation: insights from integrated studiesSemantic proximity Read ↗

Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthmaSemantic proximity Read ↗

Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in AsthmaSemantic proximity Read ↗

Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthmaSemantic proximity Read ↗

Single-cell RNA Sequencing Analysis of Sputum Cell Transcriptomes Reveals Pathways and Communication Networks That Contribute to the Pathogenesis of AsthmaSemantic proximity Read ↗

Association of Differential Mast Cell Activation with Granulocytic Inflammation in Severe Asthma.Semantic proximity Read ↗

Single-cell transcriptomic analysis reveals key immune cell phenotypes in the lungs of patients with asthma exacerbation.Semantic proximity Read ↗

IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in AsthmaSemantic proximity Read ↗

Integration of Airway Inflammation and Remodeling Mechanisms Specific to Eosinophilic Asthma Through Differential Co-Expression of Genes in Bronchial Brush Biopsy SamplesSemantic proximity Read ↗

Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohortsSemantic proximity Read ↗

The Utility of Resolving Asthma Molecular Signatures Using Tissue-Specific Transcriptome DataSemantic proximity Read ↗

The many paths to asthma: phenotype shaped by innate and adaptive immunitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.