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Article

Genetically predicted associations between blood cell perturbation responses and bronchiectasis through immune mediation: A Mendelian Randomization study.

Respiratory medicine - 1 Mar 2026

Han Jiahui, Yan Yibo, Du Zhongye, Huang Haizhu, Yan Xuexin, Zhou Chuanlin, Lei Yanmei, Zheng Shaochu, Bao Chongxi, Jiang Yun, Wu Xiaopu, Lu Wei, Zhou Yue, Zhang Liangmin, He Rongquan, Chen Gang, Luo Jin, Kong Jinliang

Abstract excerpt

BACKGROUND: Bronchiectasis is a chronic airway disease characterized by persistent inflammation and structural damage, with substantial clinical and etiologic heterogeneity. Although previous studies have identified associations between blood cells and bronchiectasis, the causal relationships remain unclear. Moreover, the mechanisms underlying blood cell perturbation responses and their potential mediation by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41643786
DOI: 10.1016/j.rmed.2026.108701

Genes

CD38

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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