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Article

The Utility of Resolving Asthma Molecular Signatures Using Tissue-Specific Transcriptome Data

9 Sept 2020

Abstract excerpt

Abstract An integrative analysis focused on multi-tissue transcriptomics has not been done for asthma. Tissue-specific DEGs remain undetected in many multi-tissue analyses, which influences identification of disease-relevant pathways and potential drug candidates. Transcriptome data from 609 cases and 196 controls, generated using airway epithelium, bronchial, nasal, airway macrophages, distal lung fibroblasts,...

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PMID: 32900903
DOI: 10.1534/g3.120.401718

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