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Article

Fluoroquinolone resistance mutations among Mycobacterium tuberculosis and their interconnection with treatment outcome.

International journal of mycobacteriology - 1 Jan 2000

Dixit Ramakant, Mohan Emil, Gupta Ankur, Gupta Priyanka Soni, Patni Tarun, Goyal Mukesh, Meena Roshan Kumar

Abstract excerpt

Background: Fluoroquinolone (FQ) antibiotics are among the most potent second-line antitubercular drugs these days. The aim of the study was to analyze the frequency and pattern of genetic mutation in preextensive (pre-XDR) and extensively drug-resistant Mycobacterium tuberculosis using second-line line probe assay (LPA) and to compare drug-resistant mutations with different treatment outcomes. Methods: Sputum,...

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PMID: 37721235
DOI: 10.4103/ijmy.ijmy_116_23

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