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Article

Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran.

BMC infectious diseases - 1 Jun 2020

Sayadi Mahdieh, Zare Hosna, Jamedar Saeed Amel, Hashemy Seyed Isaac, Meshkat Zahra, Soleimanpour Saman, Hoffner Sven, Ghazvini Kiarash

Abstract excerpt

BACKGROUND: Fluoroquinolones are broad-spectrum antibiotics that are recommended, and increasingly important, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Resistance to fluoroquinolones is caused by mutations in the Quinolone Resistance Determining Region (QRDR) of gyrA and gyrB genes of Mycobacterium tuberculosis. In this study, we characterized the phenotypic and genotypic resistance to...

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Identifiers

PMID: 32487030
DOI: 10.1186/s12879-020-05112-5
PMCID: PMC7268510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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