Back to search

Article

Fluoroquinolone resistance and mutational profile of gyrA in pulmonary MDR tuberculosis patients

2020-04-17

Abstract excerpt

<h4>Background: </h4> Fluoroquinolones (FQs) are potential drugs that inhibit DNA synthesis and are used in the treatment of multidrug-resistant tuberculosis (TB) and short-term anti-TB regimens. In recent years, a high proportion of FQ resistance has been observed in Mycobacterium tuberculosis isolates. The development of FQ resistance in multidrug-resistant TB negatively impacts patient treatment outcome and is...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
74698a1a-d911-578c-b309-839d6220bea8
DOI
10.21203/rs.2.15811/v4
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Fluoroquinolone resistance and mutational profile of gyrA in pulmonary MDR tuberculosis patientsDOI 10.21203/rs.2.15811/v4
Fluoroquinolone resistance and mutational profile of gyrA in pulmonary MDR tuberculosis patients.Semantic proximity
Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran.Semantic proximity
Evaluation of genetic mutations associated with phenotypic resistance to fluoroquinolones, bedaquiline, and linezolid in clinical Mycobacterium tuberculosis: A systematic review and meta-analysis.Semantic proximity
Fluoroquinolone resistance mutations among Mycobacterium tuberculosis and their interconnection with treatment outcome.Semantic proximity
Risk assessment and transmission of fluoroquinolone resistance in drug-resistant pulmonary tuberculosis: a retrospective genomic epidemiology study.Semantic proximity
Frequency and geographic distribution of gyrA and gyrB mutations associated with fluoroquinolone resistance in clinical Mycobacterium tuberculosis isolates: a systematic review.Semantic proximity
Characterization of gyrA and gyrB mutations and fluoroquinolone resistance in Mycobacterium tuberculosis clinical isolates from Hubei Province, China.Semantic proximity
Emergence of Specific gyrA Mutations Associated High-Level Fluoroquinolone-Resistant Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Cases in North India.Semantic proximity
Rifampicin and rifabutin resistance in 1000 <i>Mycobacterium tuberculosis</i> clinical isolatesSemantic proximity
Molecular characterization of fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates from Shanghai, China.Semantic proximity
Alarming levels of fluoroquinolone resistance among MDR-TB patients in Poland: molecular and phenotypic analysis.Semantic proximity
Fluoroquinolone resistance and mutation profiles in Mycobacterium tuberculosis through whole genome sequencing in Fujian province, China.Semantic proximity
Select a neighboring publication to make it the new centre.