Article
Molecular characterization of mutations associated with resistance to second line drugs in Mycobacterium tuberculosis patients from Casablanca, Morocco.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2021
Momen Ghizlane, Aainouss Achraf, Lamaammal Abdelmajid, Chettioui Fouad, Blaghen Mohamed, Messoudi Malika, Belghmi Khalid, Mouslim Jamal, El Mzibri Mohammed, El Messaoudi My Driss, Khyatti Meriem, Chaoui Imane
Abstract excerpt
The emergence and spread of extensively drug-resistant tuberculosis (XDR-TB) is a serious threat to global health. Therefore, its rapid diagnosis is crucial. The present study aimed to characterize mutations conferring resistance to second line drugs (SLDs) within multidrug Mycobacterium tuberculosis (MDR-MTB) isolates and to estimate the occurrence of XDR-TB in Casablanca, Morocco. A panel of 200 MDR-TB isolates...
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