Article
Molecular characterisation of second-line drug resistance among drug resistant tuberculosis patients tested in Uganda: a two and a half-year's review.
BMC infectious diseases - 11 Apr 2022
Mujuni Dennis, Kasemire Dianah Linda, Ibanda Ivan, Kabugo Joel, Nsawotebba Andrew, Phelan Jody E, Majwala Robert Kaos, Tugumisirize Didas, Nyombi Abdunoor, Orena Beatrice, Turyahabwe Irene, Byabajungu Henry, Nadunga Diana, Musisi Kenneth, Joloba Moses Lutakoome, Ssengooba Willy
Abstract excerpt
BACKGROUND: Second-line drug resistance (SLD) among tuberculosis (TB) patients is a serious emerging challenge towards global control of the disease. We characterized SLD-resistance conferring-mutations among TB patients with rifampicin and/or isoniazid (RIF and/or INH) drug-resistance tested at the Uganda National TB Reference Laboratory (NTRL) between June 2017 and December 2019. METHODS: This was a descriptive...
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