Article
Genotypic Characterization of Drug Resistance-associated Mutations in Mycobacterium tuberculosis Using Line Probe Assays in Central India.
International journal of mycobacteriology - 1 Apr 2026
Tiwari Antisha, Gaikwad Shaina, Dangi Vishal, Agrawal Falguni, Singh Maneesh, Singh Jitendra, Khadanga Sagar, Khurana Alkesh, Purwar Shashank, Biswas Debasis, Maurya Anand Kumar
Abstract excerpt
BACKGROUND: Drug-resistant tuberculosis (TB), especially rifampicin-resistant and multidrug-resistant TB, remains a significant public health challenge worldwide. Rapid and accurate methods for molecular diagnostics, such as first-line line probe assay (FL-LPA), are recommended by the World Health Organization for early detection of Rif and isoniazid resistance. However, limited data are available comparing...
Topics
- Mycobacterium tuberculosis
- Humans
- India
- Antitubercular Agents
- Mutation
- Tuberculosis, Multidrug-Resistant
- Bacterial Proteins
- Genotype
- Rifampin
- Isoniazid