Article
Frequency of first and second-line drug resistance-associated mutations among resistant Mycobacterium tuberculosis clinical isolates from São Paulo, Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Jan 2020
Matsui Tania, Pinhata Juliana Maíra Watanabe, Rabello Michelle Christiane da Silva, Brandão Angela Pires, Ferrazoli Lucilaine, Leão Sylvia Cardoso, Viana-Niero Cristina, Oliveira Rosangela Siqueira de
Abstract excerpt
BACKGROUND Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the number of new cases of multidrug resistant TB (MDR-TB), pre extensively drug-resistant TB (pre-XDR-TB) and extensively drug-resistant TB (XDR-TB) has increased considerably worldwide. OBJECTIVES Herein, using 156 M. tuberculosis isolates from 106 patients previously classified as MDR or pre-XDR or XDR...
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