Article
Molecular characterization of mutations associated with resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients from high prevalence tuberculosis city in Morocco.
BMC infectious diseases - 27 Feb 2018
Oudghiri Amal, Karimi Hind, Chetioui Fouad, Zakham Fathiah, Bourkadi Jamal Eddine, Elmessaoudi My Driss, Laglaoui Amin, Chaoui Imane, El Mzibri Mohammed
Abstract excerpt
BACKGROUND: The emergence of extensively drug-resistant tuberculosis (XDR-TB) has raised public health concern for global TB control. Although multi drug-resistant tuberculosis (MDR- TB) prevalence and associated genetic mutations in Morocco are well documented, scarce information on XDR TB is available. Hence, the evaluation of pre-XDR and XDR prevalence, as well as the mutation status of gyrA, gyrB, rrs, tlyA...
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