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Article

BRCA1 and BRCA2 mutations and their clinical relevance in selected women diagnosed with triple-negative breast cancer in Kenya: a descriptive cross-sectional study.

The Pan African medical journal - 1 Jan 2023

Rioki Josephine Nyabeta, Muchiri Lucy, Mweu Marshal, Nyagol Joshua, Songok Elijah, Mwangi Joseph, Oyaro Micah, Ong'ang'o Laban Bwire, Rogena Emily

Abstract excerpt

Introduction: triple-negative breast cancer (TNBC) is a heterogeneous breast cancer type with a poor prognosis. About 25% of TNBC patients carry breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2) mutations. Screening for BRCA mutations would facilitate early detection and initiation of personalized therapy, thus improving prognosis. However, this has not been explored in our population. We aimed at...

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Identifiers

PMID: 37719058
DOI: 10.11604/pamj.2023.45.102.36431
PMCID: PMC10504444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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