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Article

Prevalence of BRCA mutations among women with triple-negative breast cancer (TNBC) in a genetic counseling cohort.

Annals of surgical oncology - 1 Oct 2013

Greenup Rachel, Buchanan Adam, Lorizio Wendy, Rhoads Keelia, Chan Salina, Leedom Tracey, King Robin, McLennan Jane, Crawford Beth, Kelly Marcom P, Shelley Hwang E

Abstract excerpt

BACKGROUND: Revised NCCN guidelines recommend that women ≤60 years with triple-negative breast cancer (TNBC) be referred for consideration of genetic counseling. Small, homogeneous samples have limited evaluation of BRCA mutation prevalence among different ethnicities affected by TNBC subtype. We sought to determine whether the prevalence of BRCA mutations within a TNBC cohort differs by demographic factors....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23975317
DOI: 10.1245/s10434-013-3205-1

Genes

BRCA1
BRCA2

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Research trail→

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Prevalence of BRCA mutations among women with triple-negative breast cancer (TNBC) in a genetic counseling cohort.PMID 23975317Read ↗

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Adherence to NCCN Guidelines for Genetic Testing in Breast Cancer Patients: Who Are We Missing?Semantic proximity Read ↗

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