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Characteristics of breast cancer patients tested for germline BRCA1/2 mutations by next-generation sequencing in Ramathibodi Hospital, Mahidol University.

Cancer reports (Hoboken, N.J.) - 1 Jan 2023

Oranratnachai Songporn, Yamkaew Watchalawalee, Tunteeratum Atchara, Sukarayothin Thongchai, Iemwimangsa Nareenart, Panvichien Ravat

Abstract excerpt

INTRODUCTION: Germline mutations in BRCA1/2 are the most common cause of hereditary breast and ovarian cancer (HBOC) syndrome. Few studies published during the past decade reported the prevalence of germline BRCA mutations in Asian patients with breast cancer. We aimed to assess the prevalence and characteristics of Thai patients with breast cancer with germline BRCA1/2 mutations. METHODS: We retrospectively...

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PMID: 35778884
DOI: 10.1002/cnr2.1664
PMCID: PMC9875646

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