Article
Evaluation of BRCA1/2 mutational status among German and Austrian women with triple-negative breast cancer.
Journal of cancer research and clinical oncology - 1 Nov 2015
Muendlein Axel, Rohde Bettina H, Gasser Klaus, Haid Anton, Rauch Stephanie, Kinz Elena, Drexel Heinz, Hofmann Wera, Schindler Verena, Kapoor Rita, Decker Thomas, Lang Alois H
Abstract excerpt
PURPOSE: Testing for BRCA1 and BRCA2 mutations in breast cancer patients is used to identify the risk of second primary cancers and the risk of cancer in the patients' family. Women with triple-negative breast cancer (TNBC) are thought to be more likely to be BRCA1/2 mutation carriers, but most national guidelines for genetic testing, including those used in Germany and Austria, do not consider receptor triple...
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