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Article

Identification of BRCA1 and BRCA2 Germline Mutations in Female Breast Cancer Patients Using Next Generation Sequencing.

Asian Pacific journal of cancer prevention : APJCP - 1 Feb 2026

Swellam Menha, Khalifa Mohamed K, Nageeb Amira M, Sayed Mahmoud Magda, Hashim Maha, Alisslam I A Alshazly Aliaa, Mahfouz Magdy E, Ez ElArab Lobna R, Mahmoud Madyha H, Emam Sobeih Mohamed

Abstract excerpt

BACKGROUND: Breast cancer is the most common cancer affecting females according to WHO 2020 report, with BRCA1 and BRCA2 identified as the major tumor suppressor genes linked to disease susceptibility. Hence, the purpose of the current study was to investigate germline mutations among these genes in a group of Egyptian female breast cancer patients. METHODS: Blood samples from primary breast cancer patients...

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Source

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Identifiers

PMID: 41660915
DOI: 10.31557/APJCP.2026.27.2.575
PMCID: PMC13492721

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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