Genetic testing in women with breast cancer: implications for treatment.

Abstract excerpt

INTRODUCTION: Mutations in either the BRCA1 or BRCA2 genes are responsible for approximately 42,000 cases of breast cancer annually. Identifying these germline mutations in a woman with breast cancer is important because it can influence her immediate and long-term management and has important implications for other family members. Areas covered: This review highlights how treatment-focussed genetic testing for...

Topics

• BRCA1 Protein
• BRCA2 Protein
• Breast Neoplasms
• Female
• Genetic Predisposition to Disease
• Genetic Testing
• Germ-Line Mutation
• Humans