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Article

TOMM40 '523 Genotype Distinguishes Patterns of Cognitive Improvement for Executive Function in APOEɛ3 Homozygotes.

Journal of Alzheimer's disease : JAD - 1 Jan 2023

Watts Amber, Haneline Stephen, Welsh-Bohmer Kathleen A, Wu Jingtao, Alexander Robert, Swerdlow Russell H, Burns Daniel K, Saunders Ann M

Abstract excerpt

BACKGROUND: TOMM40 '523 has been associated with cognitive performance and risk for developing Alzheimer's disease independent of the effect of APOE genotype. Few studies have considered the longitudinal effect of this genotype on change in cognition over time. OBJECTIVE: Our objective was to evaluate the relationship between TOMM40 genotype status and change in cognitive performance in the TOMMORROW study, which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37718796
DOI: 10.3233/JAD-230066
PMCID: PMC10578241

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