Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.

doi:10.1016/j.jalz.2017.03.009

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Article

Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Nov 2017

Willette Auriel A, Webb Joseph L, Lutz Michael W, Bendlin Barbara B, Wennberg Alexandra M, Oh Jennifer M, Roses Allen, Koscik Rebecca L, Hermann Bruce P, Dowling N Maritza, Asthana Sanjay, Johnson Sterling C

Abstract excerpt

INTRODUCTION: Family history (FH) of Alzheimer's disease (AD) affects mitochondrial function and may modulate effects of translocase of the outer mitochondrial membrane 40 kDa (TOMM40) rs10524523 ('523) poly-T length on memory decline. METHODS: For 912 nonapolipoprotein ε4 middle-aged adults and 365 aged adults across the AD spectrum, linear mixed models gauged FH and TOMM40 '523 interactions on memory and global...

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Identifiers

PMID: 28549947
DOI: 10.1016/j.jalz.2017.03.009
PMCID: PMC5810361

Genes

TOMM40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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