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Article

New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics.

Current neurology and neuroscience reports - 1 May 2016

Lutz Michael W, Crenshaw Donna, Welsh-Bohmer Kathleen A, Burns Daniel K, Roses Allen D

Abstract excerpt

Clinical trials for Alzheimer's disease are now focusing on the earliest stages of the disease with the goal of delaying dementia onset. There is great utility in using genetic variants to identify individuals at high age-dependent risk when the goal is to begin treatment before the development of any cognitive symptoms. Genetic variants identified through large-scale genome-wide association studies have not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27039903
DOI: 10.1007/s11910-016-0643-8

Genes

APOE
TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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