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Article

Association of ERCC family mutations with prognosis and immune checkpoint inhibitors response in multiple cancers.

Scientific reports - 25 Aug 2023

Chen Chao, Liu Haozhen, Li Yanlin, Liu Jixian

Abstract excerpt

The proteins encoded by the excision repair cross-complementing (ERCC) family are pivotal in DNA damage repair and maintaining genome stability. However, the precise role of the ERCC family in tumor prognosis and the effectiveness of immune checkpoint inhibitors (ICI) therapy remain uncertain. This study aimed to explore the connection between ERCC mutations and prognosis as well as the response to ICI. We...

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Identifiers

PMID: 37626083
DOI: 10.1038/s41598-023-40185-7
PMCID: PMC10457344

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