Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Down syndrome and leukemia: from basic mechanisms to clinical advances

13 Jul 2023

Abstract excerpt

Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of developing acute leukemia compared to the overall population. Many studies investigating the link between trisomy 21 and leukemia initiation and progression have been conducted over the last two decades. Despite improved treatment regimens and significant progress in iden - tifying genes on chromosome 21 and the mechanisms by which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Down syndrome and intellectual disability research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37439336
DOI: 10.3324/haematol.2023.283225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Down syndrome and leukemia: from basic mechanisms to clinical advancesPMID 37439336Read ↗

Down syndrome and leukemia: An insight into the disease biology and current treatment options.Semantic proximity Read ↗

Down syndrome-associated leukaemias: current evidence and challengesSemantic proximity Read ↗

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome.Semantic proximity Read ↗

Myeloid Leukemia in Down SyndromeSemantic proximity Read ↗

Down syndrome and leukemia: insights into leukemogenesis and translational targets.Semantic proximity Read ↗

Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndromeSemantic proximity Read ↗

Down syndrome preleukemia and leukemia.Semantic proximity Read ↗

Hematological disorders in children with Down syndrome.Semantic proximity Read ↗

Predispositions to Leukemia in Down Syndrome and Other Hereditary Disorders.Semantic proximity Read ↗

Suspicions regarding the genetic inheritance of acute lymphoblastic leukemia in patients with down syndrome.Semantic proximity Read ↗

Leukemogenesis in infants and young children with trisomy 21.Semantic proximity Read ↗

Acute leukemia in children with Down syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.