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Myeloid Leukemia in Down Syndrome

1 Jan 2011

Abstract excerpt

Although adults with Down syndrome (DS) show a decreased incidence of cancer compared to individuals without DS, children with DS are at an increased risk of leukemia. Nearly half of these childhood leukemias are classified as acute megakaryoblastic leukemia (AMKL), a relatively rare subtype of acute myeloid leukemia (AML). Here, we summarize the clinical features of myeloid leukemia in DS, review recent research...

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PMID: 22150305
DOI: 10.1615/critrevoncog.v16.i1-2.40

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