Article
Predispositions to Leukemia in Down Syndrome and Other Hereditary Disorders.
Current treatment options in oncology - 1 Jul 2017
Saida Satoshi
Abstract excerpt
OPINION STATEMENT: Leukemia is the most common pediatric cancer and accounts for approximately one third of childhood malignancies. There are germline genetic alterations that significantly increase the risk of developing hematopoietic malignancies in childhood. In this review, we describe a number of these hereditary disorders and their clinical features. These predispositions to cancer syndromes can be...
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