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Article

Down syndrome preleukemia and leukemia.

Pediatric clinics of North America - 1 Feb 2015

Maloney Kelly W, Taub Jeffrey W, Ravindranath Yaddanapudi, Roberts Irene, Vyas Paresh

Abstract excerpt

Children with Down syndrome (DS) and acute leukemias acute have unique biological, cytogenetic, and intrinsic factors that affect their treatment and outcome. Myeloid leukemia of Down syndrome (ML-DS) is associated with high event-free survival (EFS) rates and frequently preceded by a preleukemia condition, the transient abnormal hematopoiesis (TAM) present at birth. For acute lymphoblastic leukemia (ALL), their...

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Identifiers

PMID: 25435116
DOI: 10.1016/j.pcl.2014.09.009

Genes

EFS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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