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Article

Suspicions regarding the genetic inheritance of acute lymphoblastic leukemia in patients with down syndrome.

Journal of mother and child - 1 Mar 2022

Behluli Emir, Nuhii Nexhibe, Liehr Thomas, Temaj Gazmend

Abstract excerpt

Children with Down syndrome (DS) are at markedly increased risk for acute lymphoblastic leukaemia (ALL). DS is caused by trisomy of chromosome 21 affecting approximately 1 in 732 newborns in the USA. ALL is the most common cancer in children and constitutes approximately 25% of cancer diagnoses among children under the age of 15. Different protocols for treatment and management of paediatric ALL are available;...

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Identifiers

PMID: 35853737
DOI: 10.34763/jmotherandchild.20222601.d-22-00002
PMCID: PMC10032328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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