Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of the APOEɛ4 Allele on the Relationship Between Tau and Amyloid-β in Early- and Late-Onset Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2023

Kang Jae Myeong, Shin Jeong-Hyeon, Kim Woo-Ram, Seo Seongho, Seo Haeun, Lee Sang-Yoon, Park Kee Hyung, Na Duk L, Okamura Nobuyuki, Seong Joon-Kyoung, Noh Young

Abstract excerpt

BACKGROUND: Little is known regarding the differential effects of the apolipoprotein E (APOE) ɛ4 on the regional topography of amyloid and tau in patients with both early-onset (EOAD) and late-onset Alzheimer's disease (LOAD). OBJECTIVE: To compare the distribution and association of tau, amyloid, and cortical thickness among groups classified by the presence of APOEɛ4 allele and onset age. METHODS: A total of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Amyloid beta-Peptides

Share to Apolipoprotein E4

Share to Apolipoproteins E

Share to Cognition

Share to Positron-Emission Tomography

Source

Identifiers

PMID: 37393505
DOI: 10.3233/JAD-230339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of the APOEɛ4 Allele on the Relationship Between Tau and Amyloid-β in Early- and Late-Onset Alzheimer's Disease.PMID 37393505Read ↗

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s diseaseSemantic proximity Read ↗

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease.Semantic proximity Read ↗

Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individualsSemantic proximity Read ↗

Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individuals.Semantic proximity Read ↗

APOE interacts with tau PET to influence memory independently of amyloid PETSemantic proximity Read ↗

Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET.Semantic proximity Read ↗

ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels.Semantic proximity Read ↗

Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.Semantic proximity Read ↗

APOEε4 potentiates amyloid β effects on longitudinal tau pathology.Semantic proximity Read ↗

APOEε4 potentiates Aβ effects on longitudinal tangle accumulation via tau phosphorylationSemantic proximity Read ↗

Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease.Semantic proximity Read ↗

APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.