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Article

PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion.

The Journal of biological chemistry - 1 Aug 2023

Song Ziguo, Zhang Guiquan, Huang Shuhong, Liu Yao, Li Guanglei, Zhou Xianhui, Sun Jiayuan, Gao Pengfei, Chen Yulin, Huang Xingxu, Liu Jianghuai, Wang Xiaolong

Abstract excerpt

The rapid advances in genome editing technologies have revolutionized the study of gene functions in cell or animal models. The recent generation of double-stranded DNA cleavage-independent base editors has been suitably adapted for interrogation of protein-coding genes on the basis of introducing premature stop codons or disabling the start codons. However, such versions of stop/start codon-oriented genetic...

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Identifiers

PMID: 37343700
DOI: 10.1016/j.jbc.2023.104942
PMCID: PMC10365944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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