Article
Prime editing: current advances and therapeutic opportunities in human diseases.
Science bulletin - 30 Dec 2023
Fu Yidian, He Xiaoyu, Gao Xin D, Li Fang, Ge Shengfang, Yang Zhi, Fan Xianqun
Abstract excerpt
Gene editing ushers in a new era of disease treatment since many genetic diseases are caused by base-pair mutations in genomic DNA. With the rapid development of genome editing technology, novel editing tools such as base editing and prime editing (PE) have attracted public attention, heralding a great leap forward in this field. PE, in particular, is characterized by no need for double-strand breaks (DSBs) or...
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