Article

Comprehensive analysis of prime editing outcomes in human embryonic stem cells

2021-04-13

Abstract excerpt

Prime editing is a versatile and precise genome editing technique that can directly copy desired genetic modifications into target DNA sites without the need for donor DNA. This technique holds great promise for the analysis of gene function, disease modeling, and the correction of pathogenic mutations in clinically relevant cells such as human pluripotent stem cells (hPSCs). Here we comprehensively tested prime e...

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Literature Corpus work: 1993be37-f774-54d5-b2f7-d666bcb4d8d3
DOI: 10.1101/2021.04.12.439533

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