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Article

Targeted RNA base editing for therapeutic: mechanisms and advances

18 Aug 2025

Abstract excerpt

ABSTRACT RNA base editing, which enables RNA base modification through effector proteins guided by targeting systems, is a powerful technology to correct disease-associated point mutations. Although overshadowed by CRISPR-based genome editing, RNA editing has seen rapid development in recent years, with significant improvements in efficiency and precision. In this review, we summarize the core components of RNA...

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PMID: 41550651
DOI: 10.1016/j.pscia.2025.100089

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