Article
Association between blood pressure and different antihypertensive drugs with outcome after ischemic stroke: A Mendelian randomization study.
International journal of stroke : official journal of the International Stroke Society - 1 Dec 2023
Liu Hanchen, Zhang Xiaoxi, Zhou Yu, Nguyen Thanh N, Zhang Lei, Xing Pengfei, Li Zifu, Shen Hongjian, Zhang Yongxin, Hua Weilong, Xu Hongye, Zhu Xuan, Chen Lei, Zuo Qiao, Zhao Rui, Li Qiang, Dai Dongwei, Zhang Yongwei, Xu Yi, Huang Qinghai, Liu Jianmin, Yang Pengfei
Abstract excerpt
BACKGROUND: Observational studies suggest an association between blood pressure (BP) and functional outcomes in ischemic stroke patients but whether this is causal or due to confounding is uncertain. We used Mendelian randomization (MR) to assess causality, and also explore whether particular classes of anti-hypertensives were associated with a better outcome after ischemic stroke. METHODS: We selected genetic...
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