Article
Profiling endogenous, environmental, and infectious disease mutational signatures in blastic plasmacytoid dendritic cell neoplasms.
International journal of laboratory hematology - 1 Oct 2023
Small Corinn, Mukerjee Soham, Jangam Diwash, Gollapudi Sumanth, Singh Kunwar, Jaye David L, Aung Phyu P, Querfeld Christiane, Yao Keluo, Chisholm Karen M, Pullarkat Sheeja, Wang Sa, Gru Alejandro, Hussaini Mohammad, George Tracy I, Ohgami Robert S
Abstract excerpt
BACKGROUND: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic disease derived from plasmacytoid dendritic lineage cells. The disease typically shows skin as well as frequent bone marrow and peripheral blood involvement. However, the pathogenesis of this disease is still not well understood. While somatic point mutations and genetic rearrangements have been described in BPDCN, the types...
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