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Article

Molecular Features of Blastic Plasmacytoid Dendritic Cell Neoplasm: DNA Mutations and Epigenetics.

Hematology/oncology clinics of North America - 1 Jun 2020

Sapienza Maria Rosaria, Pileri Stefano

Abstract excerpt

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic neoplasm with a dismal prognosis and no standard therapy. In the past, its cellular ontogenesis was obscure, and BPDCN had been erroneously named CD56+/TdT+ blastic NK cell tumor and CD4+/CD56+ hematodermic neoplasm. Finally, in 2008, the BPDCN was correctly recognized as a neoplasm deriving from the malignant transformation of...

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Identifiers

PMID: 32336416
DOI: 10.1016/j.hoc.2020.01.002

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